Physical signs of psilocybin ingestion can include increased heart rate, increased blood pressure, dry mouth, pupillary dilation, facial flushing, headache, vertigo, nausea, vomiting, sweating, high body temperature, incoherent or inappropriate speech, and drowsiness along with facial paresthesia such as numbness.

When taken in small amounts the pharmacologic effects are not themselves dangerous or life-threatening. However, various unfavorable effects such as emotional destabilization and derealization that follow use may lead to loss of boundaries and risk-taking behaviors which can lead to fatal accidents. As such it is always important to remember that psychoactive mushrooms should be used in moderation and in a safe environment.

The use of psychoactive mushrooms should not be combined with substances such as alcohol, cannabis, or amphetamines because these agents all have similar effects on a user's mood, thought, and behavior and will result in "exaggerated" effects which can be dangerous for the user.

Keep away from children and pets. Do not consume while pregnant. Do not drive or operate machinery while using this product.